John Calvin in his “Short Treatise on the Holy Supper of our Lord”:

17. The Internal Substance is Conjoined with the Visible Signs

We must confess, then, that if the representation which God gives us in the Supper is true, the internal substance of the sacrament is conjoined with the visible signs; and as the bread is distributed to us by the hand, so the body of Christ is communicated to us in order that we may be made partakers of it. Though there should be nothing more, we have good cause to be satisfied when we understand that Jesus Christ gives us in the Supper the proper substance of his body and blood, in order that we may possess it fully, and possessing it have part in all his blessings. For seeing we have him, all the riches of God which are comprehended in him are exhibited to us, in order that they may be ours. Thus, as a brief definition of this utility of the Supper, we may say, that Jesus Christ is there offered to us in order that we may possess him, and in him all the fullness of grace which we can desire, and that herein we have a good aid to confirm our consciences in the faith which we ought to have in him.